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homatropine (Isopto Homatropine)
Tradename: Isopto Homatropine.
Indications:
1) cycloplegia & mydriasis for refraction
2) treatment of acute inflammatory conditions of the uveal tract
3) pre- & post-operative mydriasis
Dosage:
1) mydriasis & cycloplegia
a) 1-2 drops of 2% solution or 1 drop of 5% solution before procedure
b) repeat as needed at 5-10 minute intervals
2) uveitis: 1-2 drops (2% or 5%) BID-TID PRN 2 & 5% (5 mL, 15 mL).
Adverse effects:
1) common (> 10%)
a) blurred vision
b) photophobia
2) less common (1-10%)
a) irritation
b) increased intraocular pressure
3) uncommon (< 1%)
a) vascular congestion
b) edema
c) drowsiness
d) exudate
e) eczematoid dermatitis
f) follicular conjunctivitis
Interactions
drug interactions
drug adverse effects of parasympatholytics
General
belladonna alkaloid
cycloplegic agent
mydriatic agent
parasympatholytic (anticholinergic, antimuscarinic agent)
Properties
KINGDOM: plant
MISC-INFO: pregnancy-category C
safety in lactation ?
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Drug Information & Medication Formulary, Veterans Affairs,
Central California Health Care System, 1st ed., Ravnan et al
eds, 1998
- Kaiser Permanente Northern California Regional Drug
Formulary, 1998
Component-of
homatropine/hydrocodone (Hycodan)