HMG CoA synthase gene

5q13.3-q14

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: HMG CoA synthase MOTIF: sterol regulatory element-2 (SRE-2) SITE: -310 MOTIF-SEQUENCE: CGTCCCGC sterol regulatory element-1 (SRE-1) SITE: -290 FOR-BINDING-OF: sterol regulatory element-binding protein 1 MOTIF-SEQUENCE: CACCCTAC sterol regulatory element-1 (SRE-1) SITE: -250 FOR-BINDING-OF: sterol regulatory element-binding protein 1 MOTIF-SEQUENCE: CACCCCAC TATA box NAME: TATA box transcriptional start site exon (18) intron (17) transcriptional termination site

References

- Vallett SM et al A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene. J Biol Chem. 1996 May 24;271(21):12247-53. PMID: 8647822