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HMG CoA reductase Ab in serum

Indications: - evaluation of immune-mediated necrotizing myopathy Clinical significance: - generally associated with statin exposure [2] - may be found without immune-mediated necrotizing myopathy

Related

hydroxymethylglutaryl [HMG] CoA reductase (HMGCR)

Specific

HMG CoA reductase IgG in serum

General

serology

References

  1. Loinc
  2. Medical Knowledge Self Assessment Program (MKSAP) 18, American College of Physicians, Philadelphia 2018
  3. Musset L, Allenbach Y, Benveniste O et al Anti-HMGCR antibodies as a biomarker for immune-mediated necrotizing myopathies: A history of statins and experience from a large international multi-center study. Autoimmun Rev. 2016 Oct;15(10):983-93. Review. PMID: 27491568