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HLA class II histocompatibility antigen, DRB3-1 beta chain; MHC class I antigen DRB3*1 (HLA-DRB3-1b, HLA-DRB3)
Structure:
- heterodimer of an alpha chain & a beta chain
- belongs to the MHC class II family
- contains 1 Ig-like C1-type domain (immunoglobulin-like domain)
Compartment: membrane
Polymorphism:
- alleles of DRB3-1:
a) DRB3*0301
b) DRB3*0102
General
glycoprotein
membrane protein
Properties
SIZE: entity length = 266 aa
MW = 30 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-29}
Beta-1 {30-124}
MOTIF: cysteine residue {C44}
MODIFICATION: cysteine residue {C108}
N-glycosylation site {N48}
cysteine residue {C108}
MODIFICATION: cysteine residue {C44}
Beta-2 {125-227}
MOTIF: immunoglobulin superfamily domain {126-214}
cysteine residue {C146}
MODIFICATION: cysteine residue {C202}
cysteine residue {C202}
MODIFICATION: cysteine residue {C146}
transmembrane domain {228-250}
Database Correlations
UniProt P79483
PFAM correlations
Kegg hsa:3125
References
UniProt :accession P79483