zinc finger & BTB domain-containing protein 48; Krueppel-related zinc finger protein 3; protein HKR3 (ZBTB48, HKR3)

Function: - binds to & regulates the J &/or S elements in MHC II promoter Structure: - belongs to the krueppel C2H2-type Zn⁺²-finger protein family - contains 1 BTB/POZ domain - contains 11 C2H2-type Zn⁺² fingers Compartment: nucleus Expression: detected in adrenal gland & neuroblastoma

General

C2H2 type zinc finger protein HKR protein Zinc finger & BTB domain containing protein

Properties

SIZE: entity length = 688 aa MW = 77 kD COMPARTMENT: cell nucleus MOTIF: BTB domain {26-89} MOTIF: Zinc finger NAME: Zinc finger EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 291-313 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 319-341 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 350-372 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 378-401 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 407-430 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 436-459 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 465-487 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 493-515 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 521-544 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 550-572 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 578-600 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 165270 UniProt P10074 PFAM correlations Entrez Gene 3104 Kegg hsa:3104

References

UniProt :accession P10074