HIV-associated neutropenia

Etiology: 1) bone marrow infiltration a) granulomatous infectious process b) lymphoma 2) pharmaceutical agents a) nucleoside analogues b) trimethoprim-sulfamethoxazole c) ganciclovir d) chemotherapy for treatment of: 1] lymphoma 2] Kaposi's sarcoma Management: - granulocyte colony-stimulating factor (G-CSF) a) neutrophils count < 500/mm3 b) continue therapy until neutrophil count > 1000/mm3

General

HIV1/AIDS-associated hematologic disorder neutropenia

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998