HIV-associated anemia

Etiology: 1) anemia of chronic disease 2) infectious agents a) Mycobacterium avium complex (MAC) b) lymphoma involving the bone marrow c) granulomatous infections, especially fungal d) parvovirus B19 3) drug-induced anemia - zidovudine causes direct marrow toxicity Laboratory: 1) serum erythropoietin levels < 50 U/mL (2/3) 2) also see anemia Management: 1) recombinant erythropoietin for those patients with serum erythropoietin levels < 50 U/mL 2) intravenous immune globulin for parvovirus B19 infection

General

HIV1/AIDS-associated hematologic disorder anemia

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998