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HIV1-discordant couples
Procedure:
- use sperm from an HIV-negative donor (safest option)
- use highly active antiretroviral therapy (HAART) to suppress HIV in the man & have condomless intercourse only near ovulation while the woman is using daily preexposure prophylaxis
- collect man's sperm & "wash" to remove HIV-infected sperm; test sperm to confirm the absence of HIV, then use during intrauterine insemination or in vitro fertilization; use in conjunction with HAART & preexposure prophylaxis [1]
Related
HIV1 infection; human immunodeficiency virus-1 infection
References
- Orciari Herman A, Sofair A.
CDC Outlines Options for HIV-Discordant Couples Who Want to
Conceive.
Physician's First Watch, June, 2017
David G. Fairchild, MD, MPH, Editor-in-Chief
Massachusetts Medical Society
http://www.jwatch.org
- Kawwass JF, Smith DK, Kissin DM, et al.
Strategies for Preventing HIV Infection Among HIV-Uninfected
Women Attempting Conception with HIV-Infected Men - United
States.
MMWR Morb Mortal Wkly Rep 2017;66:554-557
https://www.cdc.gov/mmwr/volumes/66/wr/mm6621a2.htm