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HIV-1 + HIV-2 Ab + HIV-1 p24 Ag

Indications: - screening for HIV infection - identifies both HIV1 & HIV2 - presence of HIV1 p24 Ag prior to HIV1 Ab identifies HIV1 acute retroviral syndrome Interferences: - Covid-19 infection may cause false-positive HIV screening tests (4th generation) [2]

General

HIV laboratory testing

References

  1. FDA News Release. July 23, 2015. FDA approves diagnostic test to differentiate between types of HIV infection. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm455813.htm
  2. Gudipati S et al. Increase in false-positive fourth-generation human immunodeficiency virus tests in patients with coronavirus disease 2019. Clin Infect Dis 2023 May 9; [e-pub]. PMID: 37158382 https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad264/7157537
  3. Rose MR, MChida NM, Jones JL Fourth-Generation HIV Testing JAMA. Published online December 1, 2023 PMID: 38039053 https://jamanetwork.com/journals/jama/fullarticle/2812672