Search
histoplasmin (Histolyn-CYL)
Tradename: Histolyn-CYL.
Indications:
- antigen used in histoplasmosis skin testing
- diagnosis of histoplasmosis in endemic areas
- Histoplasma capsulatum [2]
- used to assess cell-mediated immunity
- used as a control in tuberculin skin testing
Dosage:
- adults
a) 0.1 mL of a 1:100 dilution into volar surface of forearm
b) induration of > 5 mm in diameter at 48-72 hours indicates a positive reaction
Injection: 0.1 mL, 1.3 mL.
Adverse effects:
- not common (1-10%)
- ulceration or necrosis may occur at the test site, pruritus, shortness of breath, urticaria
Drug interactions:
1) any live virus vaccine
2) corticosteroids
3) immunosuppressive agents
Related
histoplasmosis (Ohio Valley fever)
histoplasmosis skin testing
General
pharmacologic combination
antigen
References
- Kaiser Permanente Northern California Regional Drug
Formulary, 1998
- Deprecated Reference
- Department of Veterans Affairs, VA National Formulary