HIRA-interacting protein 3 (HIRIP3)

Function: - role in chromatin function & histone metabolism via its interaction with HIRA & histones - interacts with HIRA - weak interaction with histones H2B & H3 Compartment: nucleus Alternative splicing: named isoforms=2 Expression: - widely expressed - isoform 1 is predominant in skeletal muscle - isoform 2 is predominant in liver & heart

General

nuclear protein phosphoprotein

Properties

SIZE: MW = 62 kD entity length = 556 aa COMPARTMENT: cell nucleus MOTIF: Thr phosphorylation site {T84} Ser phosphorylation site {S87} Ser phosphorylation site {S102} Ser phosphorylation site {S125} glutamate-rich region {129-253} MOTIF: glutamate residue (SEVERAL) Ser phosphorylation site {S159} Ser phosphorylation site {S160} Ser phosphorylation site {S196} Ser phosphorylation site {S199} Ser phosphorylation site {S223} Ser phosphorylation site {S227} Ser phosphorylation site {S370} serine-rich region {398-403} MOTIF: serine residue (SEVERAL)

Database Correlations

OMIM 603365 UniProt Q9BW71

References

UniProt :accession Q9BW71