high-mobility group [HMG] protein

A group of non-histone proteins found in chromatin Function: - their role has not been definitively established - they are believed to have a role in nuclear matrix stabilization, protection of single-stranded DNA, & are required for transcription

Specific

high mobility group nucleosome-binding domain-containing protein 4; non-histone chromosomal protein HMG-17-like 3 (HMGN4, HMG17L3, NHC) high mobility group protein 20A (HMG box-containing protein 20A, HMG domain-containing protein HMGX, HMG20A, HMGX1) high mobility group protein B1; high mobility group protein 1; HMG-1; amphoterin (HMGB1, HMG1) high mobility group protein B2; high mobility group protein 2; HMG-2 (HMGB2, HMG2) high mobility group protein B3; high mobility group protein 4; HMG-4; high mobility group protein 2a; HMG-2a (HMGB3, HMG2A, HMG4) high mobility group protein B4 (HMGB4) high mobility group protein HMG-I/HMG-Y; HMG-I(Y); high mobility group AT-hook protein 1; high mobility group protein A1; high mobility group protein R (HMGA1 HMGIY) high mobility group protein HMGI-C; high mobility group AT-hook protein 2 (HMGA2 HMGIC) high-mobility group protein 1-like 2; hepatoma-derived growth factor; HDGF; HMG-1L2 (HDGF, HMG1L2) HMG domain-containing protein 4; HMG box-containing protein 4; high mobility group protein 2-like 1; protein HMGBCG (HMGXB4, HMG2L1, HMGBCG) interferon-induced 17 kD protein; contains: ubiquitin cross-reactive protein; hUCRP; interferon-induced 15 kD protein (IFP17, ISG15, G1P2, UCRP) NEDD8; ubiquitin-like protein Nedd8; neddylin; neural cell expressed developmentally down-regulated protein 8; NEDD-8 (NEDD8) non-histone chromosomal protein HMG-14; high-mobility group nucleosome-binding domain-containing protein 1 (HMGN1 HMG14) non-histone chromosomal protein HMG-17; high-mobility group nucleosome-binding domain-containing protein 2 (HMGN2, HMG17) SUMO protein (small ubiquitin-related modifier) TOX high mobility group box family ubiquitin (UBCEP2, UBB, UBC) ubiquitin-like protein FUBI (FAU)

Properties

COMPARTMENT: cell nucleus