high mobility group protein B3; high mobility group protein 4; HMG-4; high mobility group protein 2a; HMG-2a (HMGB3, HMG2A, HMG4)

Function: - binds preferentially single-stranded DNA - unwinds double stranded DNA (putative) Structure: - belongs to the HMGB family - contains 2 HMG box DNA-binding domains Compartment: nucleus (putative) Expression: expressed predominantly in placenta

General

DNA-binding protein high-mobility group [HMG] protein nonhistone chromosomal protein

Properties

SIZE: entity length = 200 aa MW = 23 kD COMPARTMENT: cell nucleus MOTIF: HMG box SITE: 9-79 HMG box SITE: 93-161 acidic region {181-200} MOTIF: acidic residue (SEVERAL)

Database Correlations

OMIM 300193 UniProt O15347 Pfam PF00505 Entrez Gene 3149 Kegg hsa:3149

References

UniProt :accession O15347