heterogeneous nuclear ribonucleoprotein A1-like protein; hnRNP core protein A1-like protein (HNRNPA1L, HNRNPA1L2)

Function: - role in the packaging of pre-mRNA into hnRNP particles - transport of poly(A) mRNA from the nucleus to the cytoplasm - may modulate splice site selection (putative) - may be a component of the spliceosome C complex Structure: contains 2 RRM (RNA recognition motif) domains Compartment: - nucleus, cytoplasm - shuttles continuously between the nucleus & cytoplasm along with mRNA - component of ribonucleosomes

Properties

SIZE: entity length = 320 aa MW = 34 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: Globular A {4-94} RNP motif NAME: RNP motif SITE: 14-97 FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif NAME: ribonucleoprotein-1 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif ribonucleoprotein-2 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif Globular B {95-185} MOTIF: RNP motif NAME: RNP motif SITE: 105-184 FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif NAME: ribonucleoprotein-1 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif ribonucleoprotein-2 motif FOR-BINDING-OF: ribonucleic acid MOTIF: ribonucleoprotein-1 motif ribonucleoprotein-2 motif glycine-rich region {195-317} MOTIF: binding site SITE: 218-240 FOR-BINDING-OF: ribonucleic acid nuclear targeting sequence {268-305}

Database Correlations

UniProt Q32P51 Pfam PF00076 Kegg hsa:1449

References

UniProt :accession Q32P51