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HERV-K 8p23.1 provirus ancestral Env polyprotein (HERV-K115 envelope protein, EnvK6 protein, [Contains: Surface protein (SU); Transmembrane protein (TM)])
Also see endogenous retroviral envelope polyprotein
Genetics:
- insertional polymorphism
- Provirus present in 16% of individuals tested
- intragenic, in first intron of DEFB107 gene
General
endogenous retroviral envelope polyprotein
glycoprotein
Properties
SIZE: MW = 79 kD
entity length = 699 aa
MOTIF: signal sequence {1-89}
MOTIF: arginine-rich region {13-20}
MOTIF: arginine residue (SEVERAL)
N-glycosylation site {N100}
N-glycosylation site {N128}
N-glycosylation site {N153}
N-glycosylation site {N274}
N-glycosylation site {N355}
N-glycosylation site {N372}
N-glycosylation site {N461}
proteolytic site {465-466}
Fusion peptide {466-486}
N-glycosylation site {N507}
N-glycosylation site {N554}
N-glycosylation site {N566}
N-glycosylation site {N585}
transmembrane domain {633-653}
Database Correlations
UniProt Q902F8
Pfam PF03056
References
UniProt :accession Q902F8