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HERV-K 7q22.1 provirus ancestral Env polyprotein; HERV-K(HML-2.HOM) envelope protein,HERV-K108 envelope protein, HERV-K(C7) envelope protein; EnvK2 protein [Contains: surface protein (SU); transmembrane protein (TM)] (ERVK6)
Also see endogenous retroviral Env protein
General
endogenous retroviral envelope polyprotein
glycoprotein
Properties
SIZE: MW = 79 kD
entity length = 699 aa
MOTIF: signal sequence {1-89}
MOTIF: arginine-rich region {13-20}
MOTIF: arginine residue (SEVERAL)
alanine-rich region {94-99}
MOTIF: alanine residue (SEVERAL)
N-glycosylation site {N100}
N-glycosylation site {N128}
N-glycosylation site {N153}
N-glycosylation site {N274}
N-glycosylation site {N355}
N-glycosylation site {N372}
N-glycosylation site {N461}
proteolytic site {465-466}
Fusion peptide {466-486}
N-glycosylation site {N507}
N-glycosylation site {N554}
N-glycosylation site {N566}
N-glycosylation site {N585}
transmembrane domain {633-653}
Database Correlations
OMIM 605626
UniProt Q69384
Pfam PF03056
References
- UniProt :accession Q69384
- Human Endogenous Retrovirus Database (HERVd);
http://herv.img.cas.cz/cgi-bin/draw_full_element.cgi?fid=41575