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HERV-K 12q14.1 provirus ancestral Env polyprotein (EnvK1 protein, [Contains: Surface protein (SU); Transmembrane protein (TM)])
Also see endogenous retroviral envelope polyprotein
Function:
- has lost its original fusogenic properties
General
endogenous retroviral envelope polyprotein
glycoprotein
Properties
SIZE: MW = 79 kD
entity length = 698 aa
MOTIF: signal sequence {1-88}
MOTIF: arginine-rich region {13-20}
MOTIF: arginine residue (SEVERAL)
alanine-rich region {93-98}
MOTIF: alanine residue (SEVERAL)
N-glycosylation site {N99}
N-glycosylation site {N127}
N-glycosylation site {N152}
N-glycosylation site {N273}
N-glycosylation site {N354}
N-glycosylation site {N371}
N-glycosylation site {N460}
proteolytic site {464-465}
Fusion peptide {465-485}
N-glycosylation site {N506}
N-glycosylation site {N553}
N-glycosylation site {N565}
N-glycosylation site {N584}
transmembrane domain {632-652}
Database Correlations
UniProt P61565
Pfam PF03056
References
- UniProt :accession P61565
- Human Endogenous Retrovirus Database (HERVd);
http://herv.img.cas.cz/cgi-bin/draw_full_element.cgi?fid=63838