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HERV-H 2q24.3 provirus ancestral Env polyprotein (Env protein HERV-H/p62, Env protein HERV-H19, HERV-H/env62, Env protein HERV-Hcl.3, [Contains: Surface protein (SU); Transmembrane protein (TM)])
Also see endogenous retroviral envelope polyprotein Ortholog in Pan troglodytes Intergenic, closest flanking genes are TAIP2 & GALNT3
General
endogenous retroviral envelope polyprotein
glycoprotein
Properties
SIZE: MW = 64 kD
entity length = 584 aa
MOTIF: signal sequence {1-35}
MOTIF: N-glycosylation site {N10}
N-glycosylation site {N47}
CXXC {64-67}
N-glycosylation site {N199}
N-glycosylation site {N222}
N-glycosylation site {N265}
N-glycosylation site {N283}
N-glycosylation site {N352}
N-glycosylation site {N370}
proteolytic site {387-388}
Fusion peptide {388-408}
CKS-17 {454-470}
CX6CC {471-479}
MOTIF: cysteine residue {C471}
MODIFICATION: cysteine residue {C478}
cysteine residue {C478}
MODIFICATION: cysteine residue {C471}
N-glycosylation site {N483}
transmembrane domain {524-544}
Database Correlations
UniProt Q9N2K0
Pfam PF00429
References
- UniProt :accession Q9N2K0
- Human Endogenous Retrovirus Database (HERVd)
http://herv.img.cas.cz/cgi-bin/draw_full_element.cgi?fid=7105