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HERV-H 2q24.1 provirus ancestral Env polyprotein (Env protein HERV-H/p59, HERV-H/env59, [Contains: Surface protein (SU); Transmembrane protein (TM)])
Also see endogenous retroviral envelope polyprotein Orthologs in Pan troglodytes, Gorilla gorilla (truncated) & Pongo pygmaeus (truncated) Intergenic, closest flanking genes are KCNJ3 & NR4A2
General
endogenous retroviral envelope polyprotein
glycoprotein
Properties
SIZE: MW = 61 kD
entity length = 555 aa
MOTIF: signal sequence {1-35}
MOTIF: N-glycosylation site {N10}
N-glycosylation site {N47}
CXXC {64-67}
N-glycosylation site {N222}
N-glycosylation site {N265}
N-glycosylation site {N283}
N-glycosylation site {N352}
N-glycosylation site {N370}
proteolytic site {387-388}
Fusion peptide {388-408}
N-glycosylation site {N475}
transmembrane domain {516-536}
Database Correlations
UniProt Q9N2J8
Pfam PF00429
References
- UniProt :accession Q9N2J8
- Human Endogenous Retrovirus Database (HERVd)
http://herv.img.cas.cz/cgi-bin/draw_full_element.cgi?fid=14990