HERV-F(c)1 Xq21.33 provirus ancestral Env polyprotein (Fc1env, HERV-Fc1env, [Contains: Surface protein (SU); Transmembrane protein (TM)])

Also see endogenous retroviral envelope polyprotein Function: - has lost its original fusogenic properties Low expression in skin, testis & trachea Orthologs in Pan troglodytes & Gorilla gorilla

General

endogenous retroviral envelope polyprotein glycoprotein

Properties

SIZE: MW = 65 kD entity length = 584 aa MOTIF: signal sequence {1-22} N-glycosylation site {N69} N-glycosylation site {N247} CXXC {251-254} N-glycosylation site {N272} N-glycosylation site {N276} N-glycosylation site {N308} N-glycosylation site {N313} N-glycosylation site {N322} N-glycosylation site {N334} N-glycosylation site {N342} N-glycosylation site {N346} proteolytic site {383-384} Fusion peptide {384-404} CKS-17 {449-465} CX6CC {466-474} MOTIF: cysteine residue {C466} MODIFICATION: cysteine residue {C473} cysteine residue {C473} MODIFICATION: cysteine residue {C466} N-glycosylation site {N478} transmembrane domain {519-539}

Database Correlations

UniProt P60507 Pfam PF00429

References

UniProt :accession P60507