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hepatitis B core antibody (HBcAb total) in serum
Etiology:
- hepatitis B exposure
Clinical significance:
1) HBcAb total rises with HBcAb IgM, but remains elevated (regardless of whether or not the patient develops chronic hepatitis B)
2) HBcAb often remain elevated for life although titers of HBcAb may decline or disappear
3) isolated anti-HBc in the absence of HBsAb or HBsAg is common in HIV-infected patients [4]
Related
hepatitis B infection
hepatitis B virus (HBV)
Specific
hepatitis B core antibody (HBcAb total) in serum from donor
hepatitis B core IgG in serum
hepatitis B core IgG+IgM in serum
hepatitis B core IgM (HBcIgM) in serum
General
hepatitis B core antibody in body fluid
hepatitis B virus (HBV) serology
References
- Laboratory Medicine: Test Selection & Interpretation.
Howanitz & Howanitz (eds), Churchill Livingstone, NY,
1991, pg 818-19
- Medical Knowledge Self Assessment Program (MKSAP) 15, 16, 18.
American College of Physicians, Philadelphia 2009, 2012, 2018.
- Hepatitis B Core Antibodies, Total
Laboratory Test Directory ARUP: 20091
http://ltd.aruplab.com/tests/pub/0020091
https://ltd.aruplab.com/Tests/Pub/0020091
- Witt MD et al.
Predictors of the isolated hepatitis B core antibody pattern
in HIV-infected and -uninfected men in the Multicenter AIDS
Cohort Study.
Clin Infect Dis 2012 Nov 30;
PMID: 23090927
Component-of
hepatitis B core Ab + surface Ab + surface Ag