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hemosiderin in urine
Indications:
- evaluation of recent episode of hemoglobinuria
- evaluation of renal involvement in hemochromatosis
Reference interval:
- < 0.1 mg/day
Principle:
- free hemoglobin is rapidly filtered by the renal glomeruli & reabsorbed in the proximal tubules where it is catabolized into ferritin & hemosiderin
- hemosiderin will appear in the urine 2-3 days after an episode of acute hemolysis that resulted in hemoglobinuria
- at this time hemoglobin in urine is often negative
Increases:
- renal involvement in hemochromatoisis
- chronic hemolysis
- prosthetic heart valves
Related
hemosiderin
Specific
hemosiderin in urine qualitative
General
hemosiderin in specimen
urine chemistry test
References
- Hemosiderin, Urine
Laboratory Test Directory ARUP: 20222