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hemin-controlled inhibitor or heme-regulated eiF 2-alpha kinase (HRI)

Interactions

molecular events

General

oligomerizing protein serine/threonine kinase

Properties

CONFIGURATION: dimer STATE: active state MOTIF: S/T phosphorylation site kinase domain MOTIF: ATP-binding site NAME: ATP-binding site cysteine residue MISC-INFO: RECOGNITION-MOTIF :SEQUENCE LSEL[S*]RR :REF " - Kemp BE, Pearson RB. Protein kinase recognition sequence motifs. Trends Biochem Sci. 1990 Sep;15(9):342-6. Review. PMID: 2238044"

References

  1. Chen & London TIBS 20:105 1995