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Haplotype Map (HapMap)

Single nucleotide polymorphisms (SNPs) mark a particular spot on the genome. The SNPs are inherited along with the genes close to them. Thus, if a particular SNP is associated with a disease, nearby genes may be associated with the disease. The HapMap may greatly facilitate our understanding of the molecular basis of disease.

General

genetics

References

  1. Altshuler D, Brooks LD, Chakravarti A, Collins FS, Daly MJ, Donnelly P; International HapMap Consortium. A haplotype map of the human genome. Nature. 2005 Oct 27;437(7063):1299-320. PMID: 16255080 - Goldstein DB, Cavalleri GL. Genomics: understanding human diversity. Nature. 2005 Oct 27;437(7063):1241-2. No abstract available. PMID: 16251937
  2. International HapMap Project http://www.hapmap.org