G-protein coupled receptor 63; PSP24-2; PSP24-beta (GPR63, PSP24B)

Function: - orphan receptor. may play a role in brain function Structure: - belongs to the G-protein coupled receptor 1 family Compartment: - cell membrane; multi-pass membrane protein Expression: - expressed in brain - expressed in frontal cortex > thalamus, caudate, hypothalamus, & midbrain

General

glycoprotein G-protein coupled receptor; serpentine receptor

Properties

SIZE: entity length = 419 aa MW = 48 kD COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-81} MOTIF: N-glycosylation site {N16} N-glycosylation site {N28} N-glycosylation site {N62} transmembrane domain {82-104} cytoplasmic loop {105-115} transmembrane domain {116-138} exoplasmic loop {139-157} transmembrane domain {158-177} cytoplasmic loop {178-196} transmembrane domain {197-216} exoplasmic loop {217-240} transmembrane domain {241-263} cytoplasmic loop {264-315} transmembrane domain {316-338} exoplasmic loop {339-352} transmembrane domain {353-375} cytoplasmic domain {376-419}

Database Correlations

OMIM 606915 UniProt Q9BZJ6 Pfam PF00001 Entrez Gene 81491 Kegg hsa:81491