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G-protein coupled receptor 61; biogenic amine receptor-like G-protein coupled receptor (GPR61, BALGR)
Function:
- orphan receptor
Structure:
- belongs to the G-protein coupled receptor 1 family
Compartment:
- cell membrane; multi-pass membrane protein
Expression:
- expressed in brain
- detected in frontal & temporal lobes, occipital pole, amygdala & hippocampus
- also expressed in testis
- low expression in many other tissues
General
glycoprotein
G-protein coupled receptor; serpentine receptor
Properties
SIZE: entity length = 451 aa
MW = 49 kD
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-44}
MOTIF: N-glycosylation site {N12}
transmembrane domain {45-67}
cytoplasmic loop {68-75}
transmembrane domain {76-98}
exoplasmic loop {99-112}
transmembrane domain {113-135}
cytoplasmic loop {136-155}
transmembrane domain {156-178}
exoplasmic loop {179-206}
transmembrane domain {207-229}
cytoplasmic loop {230-287}
transmembrane domain {288-310}
exoplasmic loop {311-324}
transmembrane domain {325-344}
cytoplasmic domain {345-451}
Database Correlations
OMIM 606916
UniProt Q9BZJ8
Pfam PF00001
Entrez Gene 83873
Kegg hsa:83873
References
OMIM :accession 606916
UniProt :accession Q9BZJ8