Contents

Search


trace amine-associated receptor 2; TaR-2; trace amine receptor 2; G-protein coupled receptor 58 (TAAR2, GPR58)

Function: - orphan receptor Structure: - belongs to the G-protein coupled receptor 1 family Compartment: - cell membrane; multi-pass membrane protein Alternative splicing: named isoforms=2 Expression: - not expressed in the pons, thalamus, hypothalamus, hippocampus, caudate, putamen, frontal cortex, basal forebrain, midbrain or liver

General

glycoprotein G-protein coupled receptor; serpentine receptor

Properties

SIZE: entity length = 351 aa MW = 40 kD COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-48} MOTIF: N-glycosylation site {N24} N-glycosylation site {N30} transmembrane domain {49-69} cytoplasmic loop {70-79} transmembrane domain {80-100} exoplasmic loop {101-118} MOTIF: cysteine residue {C116} MODIFICATION: cysteine residue {C201} transmembrane domain {119-139} cytoplasmic loop {140-162} transmembrane domain {163-183} exoplasmic loop {184-207} MOTIF: cysteine residue {C201} MODIFICATION: cysteine residue {C116} transmembrane domain {208-228} cytoplasmic loop {229-263} transmembrane domain {264-284} exoplasmic loop {285-299} MOTIF: N-glycosylation site {N289} transmembrane domain {300-322} cytoplasmic domain {323-351}

Database Correlations

OMIM 604849 UniProt Q9P1P5 Pfam PF00001 Entrez Gene 9287 Kegg hsa:9287

References

UniProt :accession Q9P1P5