Contents

Search


G protein-coupled receptor GPR45 (GPR45, PSP24-alpha, PSP24-1)

Function: - orphan receptor - may play a role in brain function Structure: belongs to the G-protein coupled receptor 1 family Compartment: cell membrane Expression: - expressed in brain; detected in the basal forebrain, frontal cortex, & caudate, but not in thalamus, hippocampus, or putamen

General

glycoprotein G-protein coupled receptor; serpentine receptor

Properties

SIZE: MW = 42 kD entity length = 372 aa COMPARTMENT: cellular membrane MOTIF: exoplasmic domain {1-38} MOTIF: N-glycosylation site {N4} N-glycosylation site {N17} N-glycosylation site {N20} transmembrane domain {39-59} cytoplasmic loop {60-75} transmembrane domain {76-96} exoplasmic loop {97-109} transmembrane domain {110-130} cytoplasmic loop {131-149} transmembrane domain {150-170} exoplasmic loop {171-198} transmembrane domain {199-219} cytoplasmic loop {220-268} transmembrane domain {269-289} exoplasmic loop {290-305} transmembrane domain {306-326} cytoplasmic domain {327-372}

Database Correlations

OMIM 604838 UniProt Q9Y5Y3 Pfam PF00001 Kegg hsa:1125

References

UniProt :accession Q9Y5Y3