Search
probable G-protein coupled receptor 12 (GPR12)
Function: orphan receptor
Structure: belongs to the G-protein coupled receptor 1 family
Compartment: cell membrane
General
glycoprotein
phosphoprotein
G-protein coupled receptor; serpentine receptor
Properties
SIZE: entity length = 334 aa
MW = 37 kD
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-46}
MOTIF: N-glycosylation site {N8}
N-glycosylation site {N24}
transmembrane domain {47-66}
cytoplasmic loop {67-78}
transmembrane domain {79-102}
exoplasmic loop {103-114}
transmembrane domain {115-136}
cytoplasmic loop {137-157}
transmembrane domain {158-177}
exoplasmic loop {178-202}
MOTIF: cysteine residue {C188}
MODIFICATION: cysteine residue {C263}
transmembrane domain {203-221}
cytoplasmic loop {222-249}
transmembrane domain {250-276}
MOTIF: cysteine residue {C263}
MODIFICATION: cysteine residue {C188}
exoplasmic loop {277-281}
transmembrane domain {282-303}
cytoplasmic domain {304-334}
MOTIF: cysteine residue {C317}
MODIFICATION: palmitate
COMPARTMENT: membrane
Ser phosphorylation site {S330}
Ser phosphorylation site {S332}
Database Correlations
OMIM 600752
UniProt P47775
Pfam PF00001
Entrez Gene 2835
Kegg hsa:2835
References
UniProt :accession P47775