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G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor, G-protein coupled receptor PGR28, GPR156, GABABL, PGR28)
Function: orphan receptor
Structure:
- Belongs to the G-protein coupled receptor 3 family, GABA-B receptor subfamily
Compartment: cell membrane
Expression:
- ubiquitous expression both in the CNS & in peripheral tissues
- very high expression in fetal brain & testis relative to other tissues
General
orphan receptor
G-protein coupled receptor; serpentine receptor
Properties
SIZE: MW = 89 kD
entity length = 814 aa
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-47}
MOTIF: N-glycosylation site {N6}
transmembrane domain {48-68}
cytoplasmic loop {69-86}
transmembrane domain {87-107}
exoplasmic loop {108-118}
transmembrane domain {119-139}
cytoplasmic loop {140-164}
transmembrane domain {165-185}
exoplasmic loop {186-222}
transmembrane domain {223-243}
cytoplasmic loop {244-257}
transmembrane domain {258-278}
exoplasmic loop {279-288}
transmembrane domain {289-309}
cytoplasmic domain {310-814}
MOTIF: coiled coil {354-390}
arginine-rich region {600-603}
MOTIF: arginine residue (SEVERAL)
serine-rich region {748-751}
MOTIF: serine residue (SEVERAL)
Database Correlations
UniProt Q8NFN8
Pfam PF00003
References
UniProt :accession Q8NFN8