Search
G-protein coupled receptor 148 (G-protein coupled receptor PGR6, brain & testis restricted GPCR, GPR148, BTR, PGR6)
Function: orphan receptor
Structure: belongs to the G-protein coupled receptor 1 family
Compartment: cell membrane
Expression: restricted to nervous system & testis
Pathology:
- detected in several tumors types, including prostate cancer
General
glycoprotein
orphan receptor
G-protein coupled receptor; serpentine receptor
Properties
SIZE: MW = 38 kD
entity length = 347 aa
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-51}
MOTIF: N-glycosylation site {N34}
transmembrane domain {52-72}
cytoplasmic loop {73-85}
transmembrane domain {86-106}
exoplasmic loop {107-130}
MOTIF: serine-rich region {107-110}
MOTIF: serine residue (SEVERAL)
transmembrane domain {131-151}
cytoplasmic loop {152-165}
transmembrane domain {166-186}
exoplasmic loop {187-214}
transmembrane domain {215-235}
cytoplasmic loop {236-261}
transmembrane domain {262-282}
exoplasmic loop {283-299}
transmembrane domain {300-322}
cytoplasmic domain {323-347}
Database Correlations
UniProt Q8TDV2
Pfam PF00001
References
UniProt :accession Q8TDV2