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G protein-coupled receptor 123 (GPR123, KIAA1828)
Function: orphan receptor
Structure:
- belongs to the G-protein coupled receptor 2 family LN-TM7 subfamily
Compartment: cell membrane
Alternative splicing: named isoforms=2
General
glycoprotein
G-protein coupled receptor; serpentine receptor
Properties
SIZE: MW = 137 kD
entity length = 1280 aa
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-740}
MOTIF: N-glycosylation site {N6}
N-glycosylation site {N67}
N-glycosylation site {N344}
transmembrane domain {741-761}
cytoplasmic loop {762-773}
transmembrane domain {774-794}
exoplasmic loop {795-804}
MOTIF: N-glycosylation site {N795}
transmembrane domain {805-825}
cytoplasmic loop {826-854}
transmembrane domain {855-875}
exoplasmic loop {876-894}
transmembrane domain {895-915}
cytoplasmic loop {916-976}
transmembrane domain {977-997}
exoplasmic loop {998-1003}
transmembrane domain {1004-1024}
cytoplasmic domain {1025-1280}
Database Correlations
OMIM 612302
UniProt Q86SQ6
Pfam PF00002
Kegg hsa:8443
References
UniProt :accession Q86SQ6