guanadrel (Hylorel)

Tradename: Hylorel. Dosage: start 5 mg PO BID, usual 25-75 mg/day Tabs: 10 & 25 mg Phmarmacokinetics: 1) bioavailability 85% 2) elimination 1/2life of 10 hours Mechanism of action: - replaces norepinephrine within secretory granules of adrenergic neurons

Interactions

drug interactions drug adverse effects of antihypertensive agents

Properties

MISC-INFO: elimination route KIDNEY pregnancy-category B safety in lactation ?

References

The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996 pg 791