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growth hormone factor 1 gene (GHF1, pituitary-specific transcription factor 1 gene, Pit-1)

Related

pituitary-specific positive transcription factor 1; PIT-1; growth hormone factor 1; GHF-1 (POU1F1, GHF1, PIT1)

General

unclassified gene

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: pituitary-specific positive transcription factor 1 MOTIF: cAMP response element (CRE) transcriptional start site exon intron transcriptional termination site

References

  1. Li S, Crenshaw EB 3rd, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature. 1990 Oct 11;347(6293):528-33. PMID: 1977085
  2. Struthers RS, Vale WW, Arias C, Sawchenko PE, Montminy MR. Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant. Nature. 1991 Apr 18;350(6319):622-4. PMID: 1826763