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growth/differentiation factor 7 (GDF-7, GDF7)
Function:
- role in the motor area of primate neocortex
Structure:
1) homodimer; disulfide-linked
2) belongs to the TGF-beta family
Compartment: secreted
General
glycoprotein
Properties
SIZE: MW = 47 kD
entity length = 450 aa
MOTIF: signal sequence {1-19}
N-glycosylation site {N83}
cysteine residue {C349}
MODIFICATION: cysteine residue {C415}
cysteine residue {C378}
MODIFICATION: cysteine residue {C447}
cysteine residue {C382}
MODIFICATION: cysteine residue {C449}
cysteine residue {C414}
MODIFICATION: cysteine residue {C-INTERCHAIN}
cysteine residue {C415}
MODIFICATION: cysteine residue {C349}
cysteine residue {C447}
MODIFICATION: cysteine residue {C378}
cysteine residue {C449}
MODIFICATION: cysteine residue {C382}
Database Correlations
OMIM 604651
UniProt Q7Z4P5
PFAM correlations
References
UniProt :accession Q7Z4P5