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growth/differentiation factor 3; GDF-3 (GDF3)
Function:
- homodimer or heterodimer (putative)
- in contrast to other members of this family, cannot be disulfide-linked
Structure: belongs to the TGF-beta family
Compartment: secreted (probable)
General
glycoprotein
growth/differentiation factor (GDF)
TGF-beta family protein
Properties
SIZE: entity length = 364 aa
MW = 41 kD
MOTIF: signal sequence {1-24}
N-glycosylation site {N112}
cysteine residue {C264}
MODIFICATION: cysteine residue {C329}
cysteine residue {C293}
MODIFICATION: cysteine residue {C361}
cysteine residue {C297}
MODIFICATION: cysteine residue {C363}
N-glycosylation site {N306}
cysteine residue {C329}
MODIFICATION: cysteine residue {C264}
cysteine residue {C361}
MODIFICATION: cysteine residue {C293}
cysteine residue {C363}
MODIFICATION: cysteine residue {C297}
Database Correlations
OMIM 606522
UniProt Q9NR23
PFAM correlations
Entrez Gene 9573
Kegg hsa:9573
References
- UniProt :accession Q9NR23
- Wikipedia; Note: GDF3 entry
http://en.wikipedia.org/wiki/GDF3