GRB2-associated-binding protein 3 (growth factor receptor bound protein 2-associated protein 3, GRB2-associated binder 3, GAB3)

Function: - unknown function - interacts with PIK3R/p85, SHP2 & GRAP2/MONA - may interact with Grb2 - phosphorylated on Tyr after macrophage colony-stimulating factor receptor (M-CSFR) stimulation Structure: - belongs to the GAB family - contains 1 PH domain

General

phosphoprotein receptor

Properties

SIZE: entity length = 586 aa MW = 66 kD MOTIF: PH domain {5-117}

Database Correlations

OMIM 300482 UniProt Q8WWW8 Pfam PF00169 Kegg hsa:1397

References

UniProt :accession Q8WWW8