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GPI inositol-deacylase (hPGAP1, PGAP1)
Function:
- role in inositol deacylation of GPI-anchored proteins
- GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from endoplasmic reticulum to Golgi
Structure: belongs to the GPI inositol-deacylase family
Compartment: endoplasmic reticulum membrane
Alternative splicing: named isoforms=4
General
glycoprotein
hydrolase
transmembrane 7c protein
Properties
SIZE: MW = 105 kD
entity length = 922 aa
COMPARTMENT: endoplasmic reticulum
MOTIF: cytoplasmic domain {1-11}
transmembrane domain {12-32}
exoplasmic loop {33-641}
MOTIF: serine residue {S174}
N-glycosylation site {N402}
transmembrane domain {642-662}
cytoplasmic loop {663-668}
transmembrane domain {669-689}
exoplasmic loop {690-733}
transmembrane domain {734-754}
cytoplasmic loop {755-817}
transmembrane domain {818-838}
exoplasmic loop {839-853}
transmembrane domain {854-874}
cytoplasmic loop {875-893}
transmembrane domain {894-914}
exoplasmic domain {915-922}
Database Correlations
UniProt Q75T13
Pfam PF07819
References
UniProt :accession Q75T13