glycoprotein-30 (gp30)

Function: - ligand for erbB2 protein - also binds to & activates EGF receptor

General

glycoprotein growth factor secreted protein

Properties

SIZE: MW = 30 kD COMPARTMENT: extracellular compartment MOTIF: glycosylation site

References

- Lupu R, Colomer R, Zugmaier G, Sarup J, Shepard M, Slamon D, Lippman ME. Direct interaction of a ligand for the erbB2 oncogene product with the EGF receptor and p185erbB2. Science. 1990 Sep 28;249(4976):1552-5. PMID: 2218496