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Golgi pH regulator A; protein GPR89A; MAPK-activating protein PM01; NF-kappa-B-activating protein 90 (GPR89A, GPHRA, GPR89, SH120, CGI-13 UNQ192/PRO218)
Function:
- voltage dependent anion channel
- acidification & functions of the Golgi involved in counter-ion conductance (putative)
Structure:
- homotrimer (putative)
- belongs to the Golgi pH regulator (TC 1.A.38) family
Compartment:
- Golgi apparatus membrane; multi-pass membrane protein (putative)
Alternative splicing: named isoforms=3
Expression:
- ubiquitous
Notes: does not seem to be able to bind GTP
General
glycoprotein
transmembrane 9 protein
Properties
SIZE: entity length = 455 aa
MW = 53 kD
COMPARTMENT: golgi
MOTIF: transmembrane domain {5-25}
transmembrane domain {46-66}
transmembrane domain {79-99}
transmembrane domain {114-134}
transmembrane domain {150-170}
N-glycosylation site {N180}
N-glycosylation site {N243}
transmembrane domain {290-310}
transmembrane domain {343-363}
transmembrane domain {378-398}
transmembrane domain {425-445}
Database Correlations
OMIM 612821
UniProt B7ZAQ6
Pfam PF12537
LOCUS-LINK correlations
References
UniProt :accession B7ZAQ6