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Golgi-associated retrograde protein complex (GARP, VFT complex, VPS fifty-three complex)
Function:
- retrograde transport of early & late endosomes to the late Golgi
Structure:
- consists of: VPS52, VPS53 & VPS54
Related
endosome (phagosome)
golgi
General
molecular complex
Properties
SUBUNITS: vacuolar protein sorting-associated protein 52
COMPARTMENT: golgi
endosome
MOTIF: coiled coil {107-127}
coiled coil {194-215}
vacuolar protein sorting-associated protein 53
COMPARTMENT: golgi
endosome
MOTIF: coiled coil {55-142}
Vacuolar protein sorting-associated protein 54
MOTIF: coiled coil {240-260}
coiled coil {480-507}
coiled coil {582-603}
References
UniProt :accession Q5VIR6
Components
vacuolar protein sorting-associated protein 52 (SAC2 suppressor of actin mutations 2-like protein, VPS52, SACM2L)
vacuolar protein sorting-associated protein 53 (VPS53)
Vacuolar protein sorting-associated protein 54 (tumor antigen SLP-8p, hepatocellular carcinoma protein 8, VPS54, HCC8)