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Glypican-5; contains: secreted glypican-5 (GPC5)
Function:
- cell surface proteoglycan that bears heparan sulfate
Structure: belongs to the glypican family
Compartment:
- cell membrane; lipid-anchor
- GPI-anchor extracellular side (putative)
- secreted, extracellular space (putative)
Expression:
- in adult, primarily expressed in the brain
- also detected in fetal brain, lung & liver
General
glypican
Properties
SIZE: entity length = 572 aa
MW = 64 kD
COMPARTMENT: plasma membrane
CELL-REGION: apical region
CELL: epithelial cell
MOTIF: signal sequence {1-24}
N-glycosylation site {N120}
N-glycosylation site {N237}
Ser glycosylation site {S441}
Ser glycosylation site {S486}
Ser glycosylation site {S495}
Ser glycosylation site {S507}
Ser glycosylation site {S509}
N-glycosylation site {N527}
Database Correlations
OMIM correlations
UniProt P78333
Pfam PF01153
Entrez Gene 2262
Kegg hsa:2262
References
- UniProt :accession P78333
- Entrez Gene :accession 2262