Search
glypican-4; K-glypican (GPC4)
Function:
- cell surface proteoglycan that bears heparan sulfate
- may be involved in the development of kidney tubules & of the central nervous system
Structure: belongs to the glypican family
Compartment:
- cell membrane; lipid-anchor
- GPI-anchor extracellular side (putative)
- secreted, extracellular space (putative)
General
glypican
Properties
SIZE: entity length = 556 aa
MW = 62 kD
COMPARTMENT: plasma membrane
CELL-REGION: apical region
CELL: epithelial cell
MOTIF: signal sequence {1-18}
Ser glycosylation site {S494}
Ser glycosylation site {S498}
Ser glycosylation site {S500}
N-glycosylation site {N514}
glycosyl phosphatidylinositol [GPI] membrane anchor {N529}
Database Correlations
OMIM 300168
UniProt O75487
Pfam PF01153
Entrez Gene 2239
Kegg hsa:2239
References
UniProt :accession O75487