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glypican-1 (GPC1)
Function:
- cell surface proteoglycan that bears heparan sulfate
- cleaved & secreted
Structure: belongs to the glypican family
Compartment:
- cell membrane; lipid-anchor
- GPI-anchor extracellular side
- secreted, extracellular space
General
glypican
Properties
SIZE: entity length = 558 aa
MW = 62 kD
COMPARTMENT: plasma membrane
CELL-REGION: apical region
CELL: epithelial cell
MOTIF: signal sequence {1-23}
Ser glycosylation site {S55}
N-glycosylation site {N79}
N-glycosylation site {N116}
Ser glycosylation site {S486}
Ser glycosylation site {S488}
Ser glycosylation site {S490}
glycosyl phosphatidylinositol [GPI] membrane anchor {N530}
Database Correlations
OMIM 600395
UniProt P35052
Pfam PF01153
Entrez Gene 2817
Kegg hsa:2817
References
UniProt :accession P35052