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glypican
Structure:
- glypicans & syndecans are two major families of cell-surface proteoglycans
- glypicans (GRIPS) are anchored by glycosyl-phosphatidylinositol (GPI) linkage
- syndecans (SLIPS) have highly conserved transmembrane regions & short cytoplasmic tails
Specific
glypican-1 (GPC1)
glypican-2; cerebroglycan (GPC2)
glypican-3; intestinal protein OCI-5; GTR2-2; MXR7; (GPC3, OCI5)
glypican-4; K-glypican (GPC4)
Glypican-5; contains: secreted glypican-5 (GPC5)
glypican-6 (GPC6)
General
glypiated protein
secreted protein
Properties
COMPARTMENT: plasma membrane
CELL-REGION: apical region
CELL: epithelial cell
MOTIF: glycosyl phosphatidylinositol [GPI] membrane anchor {C-TERMINUS}
References
- OMIM :accession 300037
- prosite :accession PS01207