glycoprotein hormone alpha 2 (thyrostimulin alpha subunit, GPHA2, GPA2, ZSIG51)

Function: - stimulates the thyroid. binds & activates THSR, leads to increased cAMP production - heterodimer with GPHB5 - glycosylated Structure: - belongs to the glycoprotein hormones subunit alpha family Compartment: secreted Expression: found in a variety of tissues

General

glycoprotein protein subunit

Properties

SIZE: entity length = 129 aa MW = 14 kD MOTIF: signal sequence {1-23} cysteine residue {C31} MODIFICATION: cysteine residue {C89} N-glycosylation site {N37} cysteine residue {C48} MODIFICATION: cysteine residue {C103} cysteine residue {C57} MODIFICATION: cysteine residue {C119} cysteine residue {C61} MODIFICATION: cysteine residue {C121} N-glycosylation site {N81} cysteine residue {C89} MODIFICATION: cysteine residue {C31} cysteine residue {C103} MODIFICATION: cysteine residue {C48} cysteine residue {C119} MODIFICATION: cysteine residue {C57} cysteine residue {C121} MODIFICATION: cysteine residue {C61}

Database Correlations

UniProt Q96T91 Kegg hsa:1705

References

UniProt :accession Q96T91