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glycine cleavage system
Function:
- catalyzes degradation of glycine
Structure:
- composed of 4 proteins:
a) glycine cleavage system P protein
b) glycine cleavage system T protein
c) glycine cleavage system L protein
d) glycine cleavage system H protein
General
mitochondrial protein
molecular complex
Properties
COMPARTMENT: mitochondria
SUBUNITS: glycine decarboxylase
MOTIF: Ser phosphorylation site {S38}
Ser phosphorylation site {S39}
cofactor-binding site [754-754]
FOR-BINDING-OF: pyridoxal phosphate
glycine cleavage system H protein
MOTIF: binding site
SITE: 107-107
FOR-BINDING-OF: Lipoyl (covalent)
glycine cleavage system T protein
MOTIF: cofactor-binding site
COFACTOR-BOUND: pyridoxal phosphate
References
- UniProt :accession P23378
- UniProt :accession P23434
- UniProt :accession P48728
Components
glycine cleavage system H protein (GCSH)
glycine cleavage system T protein; aminomethyltransferase (GCVT, AMT GCST)
glycine decarboxylase; glycine dehydrogenase [decarboxylating]; glycine cleavage system P protein (GLDC)