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glycosylation-dependent cell adhesion molecule 1 (glyCAM-1, GLYCAM1)
Function:
- binds to L-selectin on neutrophils during adhesion process
Structure: belongs to the PP3/glyCAM-1 family
Alternative splicing: named isoforms=2
Expression:
- expressed in cells harvested from milk of lactating women
- not found in other tissues [1]
- expressed on endothelial cells [2]
Note:
- could be the product of a pseudogene
- encodes aberrant truncated proteins
Related
endothelial cell
General
adhesion receptor
glycoprotein
Properties
SIZE: entity length = 47 aa
MW = 5 kD
COMPARTMENT: plasma membrane
CELL: endothelial cell
MOTIF: signal sequence {1-18}
focal adhesion site
glycosylation site
transmembrane domain
Database Correlations
UniProt Q8IVK1
References
- UniProt :accession Q8IVK1
- Harrison's Principles of Internal Medicine, 14th ed.
Fauci et al (eds), McGraw-Hill Inc. NY, 1998, pg 353