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glyburide/metformin (Glucovance)

Indications: -> treatment of type-2 diabetes mellitus Contraindications: 1) renal insufficiency 2) avoid in patients with congestive heart failure 3) caution in patient > 80 years of age 4) caution in patients with hepatic disease or excessive alcohol consumption Dosage: 1) start 1 tab PO QD 2) up to 2 tabs PO BID 3) take with meals Tabs: glyburide (mg)/metformin (mg) 1.25/250, 2.5/500, 5/500

General

pharmacologic combination

Database Correlations

PUBCHEM cid=200105

References

  1. Prescriber's Letter 7(8):48 2000
  2. Prescriber's Letter 7(9):50 2000

Components

glyburide; glibenclamide (Micronase, DiaBeta, Glynase) metformin (Glucophage)