glutamate-cysteine ligase; gamma-glutamylcysteine synthetase

Function: - sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine & L-glutamate: step 1/2 Structure: - heterodimer of a catalytic heavy chain & a regulatory light chain

General

ligase or synthetase multisubunit protein

Properties

MOTIF: active site SUBUNITS: glutamate-cysteine ligase catalytic subunit glutamate-cysteine ligase regulatory subunit

References

OMIM :accession 230450

Components

glutamate-cysteine ligase catalytic subunit; gamma-glutamylcysteine synthetase catalytic subunit (GCLC) glutamate-cysteine ligase regulatory subunit; gamma-glutamylcysteine synthetase regulatory subunit (GCLM)